3 Nov 17

FAP is a uncommon inherited gastrointestinal disease that causes hundreds to a large number of precancerous polyps to form in the colon. Approximately 35,000 people in the U.S. Carry the genetic mutation inherent to the condition. Today, without prophylactic removal of the colon, people with FAP nearly inevitably develop cancer, and there is absolutely no generally accepted pharmacological treatment available. FAP has been specified as an orphan disease beneath the U.S. Orphan Drug Act, which provides various incentives for sponsors to encourage advancement of products for uncommon diseases. Phase I research of novel therapeutics for such rare, underserved diseases tend to be permitted to enroll patients as opposed to healthy volunteers, accelerating the timeline to develop approved products potentially.The warnings undertake brand-new relevance in the aftermath of the latest Haitian earthquake, that the reported loss of life toll is more than 200,000. Dr. Steven L. Shafer of Columbia University, Editor-in-Chief of Anesthesia & Analgesia, echoes the call for hospitals and healthcare providers to prepare for and practice their response to large-scale disasters, including earthquakes. He remarks, When the ‘big one’ hits the San Andreas Fault in California or New Madrid Fault in Missouri, if we are not prepared, then we’ve failed to learn from the experiences of the Chinese doctors who responded to the Wenchuan earthquake.